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Inside the Lab That Invented the COVID-19 Vaccine

Here we are, just a year after the first news of the coronavirus we now call SARS-CoV-2 and the global pandemic known as COVID-19… and scientists have already developed more than one safe & effective vaccine. How did they do that so quickly? I visited the lab whose work directly led to these first COVID vaccines, so you can learn how basic research connects to life-saving medicine. This is how to make a COVID-19 vaccine.

Coronavirus animation courtesy of: Janet Iwasa, University of Utah, with funding from the NSF, the Coronavirus Structural Task Force and the German Federal Ministery of Research

References: Wrapp, D. et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 367, 1260–1263 (2020) doi: 10.1126/science.abb2507

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Watanabe, Y., Allen, J. D., Wrapp, D., McLellan, J. S. & Crispin, M. Site-specific glycan analysis of the SARS-CoV-2 spike. Science eabb9983 (2020) doi:10.1126/science.abb9983. ———– Special thanks to our Brain Trust Patrons: AlecZero Amory Silva Amy Sowada Baerbel Winkler Benjamin Teinby Bob Rosset Brent M. Denzel Holmes Diego Lombeida Dustin Eric Meer George gladding Karen Haskell Marcus Tuepker Oliver and Arden Bradshaw Peter Ehrnstrom Robert Young Ron Kakar Salih

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